DELAYED HYPERSENSITIVITY

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Delayed Hypersensitivity

in agriculture, an application that accounts for approximately 40% of the total production of these agents. It is obviously impossible to give detailed descriptions of the many excellent papers in this volume, but some points may be noted. From a pharmacological viewpoint, the area of structure-activity relationships is particularly well covered in regard to penicillins (K. et al.) and lincomyc...

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Delayed Hypersensitivity

Exposure to picryl guinea pig albumin with 3-6 picryl groups per mole failed to affect the ability of peritoneal exudate or peripheral blood leukocytes from sensitized donors to transfer delayed sensitivity to normal recipients. In contrast, conjugates containing 40-48 picryl groups per mole altered the ability of exposed leukocytes to transfer delayed sensitivity. Evidence is presented that hi...

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Delayed Hypersensitivity

Guinea pigs infected by intradermal injection of living toxigenic diphtheria bacilli and protected by horse antitoxic globulin, given either before or after infection, develop delayed hypersensitivity of the tuberculin type to diphtherial proteins. The highest degree of hypersensitivity is specifically directed against diphtheria toxin (or toxoid) itself, although smaller delayed skin reactions...

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Immediate hypersensitivity and delayed hypersensitivity to clopidogrel.

Clopidogrel is a new antiplatelet prescribed for the secondary prevention of atherosclerotic events. The literature shows that the clinical manifestations of clopidogrel hypersensitivity include urticaria1, skin rash2-4, and angioedema5. The precise immunological mechanism underlying clopidogrel hypersensitivity has not been established. We describe two cases of hypersensitivity reaction due to...

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Polysaccharide in Delayed Hypersensitivity

A highly purified pneumococcal polysaccharide (Type II SSS) is a very efficient inducer of delayed hypersensitivity in random-bred guinea pigs. The cellular reactivity induced by this polysaccharide administered subcutaneously in complete Freund's adjuvant is of "tuberculin type"; it increases in intensity with time after the sensitizing injection, as judged by skin tests, the macrophage inhibi...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1958

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.108.6.905